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Mu opioid receptor agonism: Tramadol binds to and activates mu opioid receptors, which are responsible for transmitting pain sensations. By stimulating these receptors, tramadol reduces the perception of pain.
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Blocks pain transmission: Tramadol's unique mechanism inhibits the reuptake of certain neurotransmitters and activates opioid receptors, effectively blocking pain transmission from the peripheral nervous system to the central nervous system.
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